Endometriosis and stem cells

Importance of Stem Cells in Endometriosis – A Menstruation Problem

              Endometriosis and stem cells.

Endometriosis is a disease related to menstruation. It happens when the endometrium, the tissue that makes up the uterine lining, migrates outside of the womb, where it shouldn’t be. The condition further results into a chronic inflammatory reaction that leads to a scar tissue, as the tissue still responds to the monthly fluctuations of a woman’s menstrual cycle. Women with endometriosis experience pain while they’re on their periods, pain in the lower abdomen, or pain during sexual intercourse, and may report also have a hard time getting pregnant. On the other hand, some women with endometriosis may not have any symptoms at all. At present, there is no known cause of endometriosis, and there is no cure.

Usually, endometriosis is found in the pelvic cavity. The endometrium tissue of a woman suffering from endometriosis can attach to any of the reproductive organs like the uterus, fallopian tubes, ovaries, uterosacral ligaments, the peritoneum, between any empty spaces in the bladder, uterus, vagina, and rectum. Endometriosis usually affects women in their reproductive years (when they’re 25 to 35 years of age), but can also affect really young women in their adolescent years.

Importance of Stem Cells in Endometriosis.

stem cell ,endometriosis,stem cell banking

Endometriosis affects 1 in 10 women on a average during their reproductive years (i.e. between the ages of 15 to 49). 10% of the total female population worldwide has endometriosis, which is approximately 177 million women around the world. The prevalence of endometriosis in women with infertility is as high as to 30–50%. The cause of endometriosis is unknown and until a few years, there was no definite cure. But recent developments in stem cell research have proved to be helpful.

In the recent years, Mesenchymal stem cells (MSCs) have been explored as a potential vehicle candidate for cell-based targeted therapies for the treatment of endometriosis. MSCs are adult stem cells that can be isolated from a various organs and tissues, such as the umbilical cord, adipose tissue, bone marrow and amniotic fluid etc. MSCs are known for their self-renewal, multipotency characteristic and also have a special potential for migrating to sites of inflammation, including tumours and ectopic endometrial lesions and shown promise as a potential therapeutic vehicle for various diseases. Researchers have been studying the the characteristics of human endometrium-derived mesenchymal stem cells and their tropism to endometriosis for a few years now. It was found that endometrium derived mesenchymal stem cells (EMSCs) mainly gathered in endometriotic lesion and few EMSCs were observed in liver and spleen. This shows that the EMSCs have a tropism to endometriotic lesions rather than normal tissues which further indicates their potential for targeted endometriosis therapy. EMSCs have all the properties of MSCs. In conclusion, an increasing amount of evidence suggests that EMSCs can be used for regenerative medicine and that they can be used as an immune regulator to reduce inflammation in the coming years.

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Umbilical cord pool bank

Advance Guide Of Umbilical Cord Blood Banking You Must Know in 2019.

“Community Umbilical Cord Blood Banking helps the grandparents, parents as well as siblings accessing stem cells from the community pool”

Cord Blood Banking help provide your family with unique usage and retrieval benefits. while you access the preserved cord blood units for stem cell transplants.

For the first time in India, community stem cell banking has been launched by Mycord, Gurgaon. which would allow sharing of the preserved umbilical cord stem cells among the community of parents.This concept is the most precise way of banking the umbilical cord for therapeutic use.

Benefits Of Stem Cell Banking In India :-

  • More than 95% blood related diseases are treatable by donor cord available in same ethnic pool.
  • Highest Probability of finding matching stem cells from the community banking.
  • Less than 5% blood related diseases are treatable using your own cord in addition to the above 95%.
  • HLA matches to find an allogeneic matched cord for transplant is done before storing the sample.
  • For every cord that is stored in a cord blood bank a best matched cord is provided from the pool.
  • Family benefits the most: Immediate family members of the baby whose stem cells are preserved at birth with My cord Community Stem Cell banking program can be benefited.
  • No cost for accessing stem cells: Community members don’t have to pay for accessing stem cells for transplant.

How does the Mycord community stem cell banking work?

The parents preserve their child’s umbilical cord stem cells with Mycord & join in the community. These stored stem cells forms a collective common pool of cord blood stem cell units. The preserved cord blood stem cell units can be accessed by any member of the community including the parents when needed.

Related : Is Stem Cell Banking Worth It?

My cord has offers many additional benefits, which allows people who have not banked cord blood to get access to matched cord blood stem cells (at an extra cost).

This type of storage and sharing helps parents and siblings to access stem cells from the community pool.Thus providing a comprehensive family benefit for treatments. Nor, surprisingly, community banking has an edge over both private and public stem cell banks.It provides collective family benefit, unlike private stem cell banking.

Also Read : Which One Is More Beneficial Pool Banking Or Private Banking?